Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.46 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27853457 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL24089780 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL11653026 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL667301 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL21160714 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL21234916 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL9242662 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL9242661 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL27530922 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 | |
| SCHEMBL540323 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTPTP4A3PTP4A2PTP4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489324-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | East China University of Science and Technology (CN) | 2019-05-29 | — | — | EP | disclosed |