Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892797 | 0.79 | DRD2 (0.58) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL6650020 | 0.73 | HRH3 (0.33) | HRH1DRD1DRD3 | |
| SCHEMBL12844288 | 0.72 | HRH1 (0.65) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11754849 | 0.71 | HRH1 (1.00) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL6652606 | 0.70 | P2RX7 (0.35) | — | |
| SCHEMBL22342357 | 0.70 | HRH1 (0.46) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL4909149 | 0.70 | SLC6A2 (0.48) | HRH1DRD1DRD3 | |
| SCHEMBL5599102 | 0.70 | HRH3 (0.33) | HRH1DRD1DRD3 | |
| SCHEMBL3066804 | 0.70 | HRH1 (0.56) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL8698766 | 0.69 | HRH1 (0.69) | HRH1DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |