Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.44 |
| ▸ | PDE4A | P27815 | 15/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677308 | 0.88 | PDE4A (0.42) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL6675416 | 0.88 | KDM4E (0.43) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL7026709 | 0.88 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL6673809 | 0.87 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL8409717 | 0.83 | KDM4E (0.46) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL6673366 | 0.83 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DGAA | |
| SCHEMBL7031802 | 0.80 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DGAA | |
| SCHEMBL7088560 | 0.79 | KDM4E (0.50) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL6675937 | 0.77 | ALDH1A1 (0.51) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL6672335 | 0.77 | MAPT (0.49) | KDM4EUSP2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | disclosed |
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | disclosed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | disclosed |