Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 6/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026709 | 0.92 | PDE4B (0.41) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL7319925 | 0.89 | KDM4E (0.61) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL6672335 | 0.80 | MAPT (0.49) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL7088468 | 0.79 | PDE4B (0.48) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL6673141 | 0.79 | PDE4B (0.44) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL8409717 | 0.78 | KDM4E (0.46) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL6675416 | 0.76 | KDM4E (0.43) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL7093510 | 0.76 | MTNR1A (0.56) | ALDH1A1HPGDPDE4BPDE4APDE4C | |
| SCHEMBL6673781 | 0.76 | ALDH1A1 (0.49) | KDM4EUSP2ALDH1A1MAPTHPGD | |
| SCHEMBL6677308 | 0.75 | PDE4A (0.42) | KDM4EUSP2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814809-B1 | ARYL THIOXANTHINES | EURO CELTIQUE SA (LU) | 2003-08-13 | — | — | EP | disclosed |
| US-6440979-B1 | Aryl isoguanines | EURO-CELTIQUE, S.A. (LU) | 2002-08-27 | — | — | US | disclosed |
| US-6090816-A | ANTIASTHMA AGENTS | EURO-CELTIQUE S.A. (LU) | 2000-07-18 | — | — | US | disclosed |
| US-6066641-A | PHOSPHODIESTERASES AS MOLECULAR TARGETS FOR ANTI-ASTHMATIC AGENTS | EURO-CELTIQUE S.A. (LU) | 2000-05-23 | — | — | US | disclosed |
| WO-1996018399-A1 | ARYL THIOXANTHINES | EURO-CELTIQUE, S.A. (LU) | 1996-06-20 | — | — | WO | disclosed |
| EP-0515535-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1996-01-17 | — | — | EP | disclosed |