Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672974 | 0.86 | RARA (0.47) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6693165 | 0.84 | HDAC3 (0.48) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL6673833 | 0.75 | RARA (0.53) | LMNAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL24132657 | 0.75 | MAPT (0.49) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL6675739 | 0.75 | SMN1; SMN2 (0.44) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL9543676 | 0.72 | MAPT (0.38) | MAPTKDM4ELMNAALDH1A1KMT2A | |
| SCHEMBL6674449 | 0.72 | MEN1 (0.55) | LMNAMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL6673464 | 0.71 | RAB9A (0.59) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL522695 | 0.71 | KDM4E (0.57) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL6676184 | 0.70 | POLB (0.49) | MAPTKDM4ELMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862555-B1 | SUBSTITUTED ARYL OR HETEROARYLAMIDES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN INC (US) | 2004-10-20 | — | — | EP | claimed |
| US-20020091262-A1 | Substituted aryl or heteroarylamides having retinoid-like biological activity | ALLERGAN | 2002-07-11 | — | — | US | claimed |
| EP-0862555-A1 | SUBSTITUTED ARYL OR HETEROARYLAMIDES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | Allergan (US) | 1998-09-09 | — | — | EP | claimed |
| US-5663357-A | COMPOUNDS FOR TREATMENT OF SKIN DISORDERS | ALLERGAN (US) | 1997-09-02 | — | — | US | claimed |
| WO-1997019062-A1 | SUBSTITUTED ARYL OR HETEROARYLAMIDES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1997-05-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091262-A1 | Substituted aryl or heteroarylamides having retinoid-like biological activity | CCR8, RXRA, CBR1 | MAPT 4839/4885KDM4E 2986/4885LMNA 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.