Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673393 | 0.81 | CHRM3 (0.41) | CHRM3ALDH1A1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL5138276 | 0.73 | LMNA (0.49) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL6673388 | 0.69 | PTPN11 (0.45) | CHRM3CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL16215600 | 0.69 | CARM1 (0.57) | CHRM3CYP3A4CYP1A2CYP2D6CHRM2 | |
| SCHEMBL10371522 | 0.68 | CHRM3 (0.47) | CHRM3LMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL2368807 | 0.66 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL3803498 | 0.64 | MCHR1 (0.46) | CHRM3ALDH1A1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL14125434 | 0.63 | CYP2D6 (0.86) | CHRM3ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL14128808 | 0.63 | CYP2D6 (0.86) | CHRM3ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL3869035 | 0.63 | PIM1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421074-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003010158-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-02-06 | — | — | WO | disclosed |