Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPA | Q15257 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241824 | 0.77 | BCAT2 (0.49) | LMNAALDH1A1PRKCZHPGDMEN1 | |
| SCHEMBL5138278 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL2368807 | 0.73 | ALDH1A1 (0.67) | LMNAALDH1A1PRKCZHPGDMEN1 | |
| SCHEMBL9532619 | 0.73 | MEN1 (0.50) | LMNAALDH1A1PRKCZHPGDMEN1 | |
| SCHEMBL6673385 | 0.73 | CHRM3 (0.45) | LMNAALDH1A1PRKCZHPGDMEN1 | |
| SCHEMBL2368666 | 0.72 | RAB9A (0.55) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1190649 | 0.71 | PRKCZ (0.80) | LMNAALDH1A1PRKCZHPGDMEN1 | |
| SCHEMBL31526164 | 0.71 | LMNA (0.62) | LMNAALDH1A1PRKCZHPGDMEN1 | |
| SCHEMBL31618843 | 0.71 | LMNA (0.62) | LMNAALDH1A1PRKCZHPGDMEN1 | |
| SCHEMBL23580345 | 0.69 | LMNA (0.73) | LMNAALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002246-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING AN IKK2 INHIBITOR AND A SECOND ACTIVE INGRDIENT. | ASTRAZENECA AB (SE) | 2008-01-03 | — | — | WO | disclosed |