Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MTTP | P55157 | 13/20 | 0.46 |
| ▸ | APOB | P04114 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678708 | 0.84 | MTTP (0.48) | ALDH1A1HPGDKMT2AMTTPAPOB | |
| SCHEMBL6673930 | 0.78 | MTTP (0.51) | MTTPAPOBGAA | |
| SCHEMBL6673563 | 0.78 | MTTP (0.47) | ALDH1A1HPGDKMT2AMTTPAPOB | |
| SCHEMBL31393757 | 0.74 | CHRNB2 (0.71) | ALDH1A1MTTPAPOBHTTGAA | |
| SCHEMBL7083817 | 0.74 | HTT (0.56) | ALDH1A1MTTPAPOBHTTNTRK1 | |
| SCHEMBL6278519 | 0.72 | MTTP (0.55) | ALDH1A1MTTPAPOBGAA | |
| SCHEMBL6675345 | 0.72 | MTTP (0.49) | MTTPAPOBGAA | |
| SCHEMBL6673562 | 0.72 | MTTP (0.47) | MTTPAPOBGAA | |
| SCHEMBL6692224 | 0.72 | APOB (0.51) | ALDH1A1MTTPAPOBHTTGAA | |
| SCHEMBL6850836 | 0.71 | GAA (0.61) | ALDH1A1MTTPAPOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465613-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057205-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-07-17 | — | — | WO | disclosed |