Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 5/20 | 0.44 |
| ▸ | PLG | P00747 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670339 | 1.00 | F2 (0.48) | F2PRSS1CMA1PLGITGB3 | |
| SCHEMBL6670351 | 0.93 | ITGB3 (0.48) | F2PRSS1CMA1PLGITGB3 | |
| SCHEMBL8740397 | 0.92 | F2 (0.42) | F2PRSS1CMA1PLGITGB3 | |
| SCHEMBL8366341 | 0.91 | F2 (0.56) | F2PRSS1CMA1PLGCTRC | |
| SCHEMBL6669956 | 0.88 | F2 (0.44) | F2PRSS1PLGPLAT | |
| SCHEMBL7371676 | 0.88 | F2 (0.64) | F2PRSS1CMA1PLGCTRC | |
| SCHEMBL8361533 | 0.85 | F2 (0.44) | F2PRSS1PLGPLAT | |
| SCHEMBL7463324 | 0.85 | F2 (0.60) | F2PRSS1PLGPLAT | |
| SCHEMBL6669444 | 0.85 | F2 (0.41) | F2PRSS1PLGPLAT | |
| SCHEMBL9450495 | 0.83 | ITGB3 (0.44) | F2PRSS1CMA1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627925-B1 | TRYPSIN INHIBITORS | DENDREON CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-5714580-A | PROTECTING ALDEHYDE OF AMINOALDEHYDE (I.E. ARGININAL) WITH 4-(DIARYLMETHYL)-SEMICARBAZIDE FOR SUBSEQUENT PEPTIDE ALDEHYDE SYNTHESIS | CORVAS INTERNATIONAL, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0627925-A4 | TRYPSIN INHIBITORS. | CORVAS INT INC (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5534498-A | TREATMENT OF PANCREATITIS | CORVAS INTERNATIONAL, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0627925-A1 | TRYPSIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993014779-A1 | TRYPSIN INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1993-08-05 | — | — | WO | disclosed |