Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 7/20 | 0.52 |
| ▸ | PLG | P00747 | 2/20 | 0.52 |
| ▸ | CTRC | Q99895 | 2/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371676 | 0.93 | F2 (0.64) | F2PRSS1CMA1PLGCTRC | |
| SCHEMBL6670339 | 0.91 | F2 (0.48) | F2PRSS1CMA1PLGCTRC | |
| SCHEMBL6673600 | 0.91 | F2 (0.48) | F2PRSS1CMA1PLGCTRC | |
| SCHEMBL8409610 | 0.88 | F2 (0.52) | F2PRSS1PLGEPHA2OPRM1 | |
| SCHEMBL9815839 | 0.84 | F2 (0.62) | F2PRSS1CMA1CTRCOPRM1 | |
| SCHEMBL29562010 | 0.84 | F2 (0.62) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL29560799 | 0.84 | F2 (0.62) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL6670351 | 0.84 | ITGB3 (0.48) | F2PRSS1CMA1PLGCTRC | |
| Efegatran SCHEMBL635674 | 0.84 | F2 (0.58) | F2PRSS1PLGEPHA2OPRM1 | |
| Hydrochloric Acid SCHEMBL7416216 | 0.84 | F2 (0.54) | F2PRSS1PLGEPHA2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955576-A | PEPTIDE ALDEHYDE ANALOGS THAT INHIBIT THROMBIN OR FACTOR XA; FOR PREVENTION OR TREATMENT OF ABNORMAL THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0684830-B1 | INHIBITORS OF THROMBOSIS | CORVAS INT INC (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5886146-A | N-ACYLATED OR SULFONATED TRIPEPTIDES FROM PROLINE, ARGININE AND AMINO ACID WITH CARBOXY OR TETRAZOLE GROUP | CORVAS INTERNATIONAL, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0627929-B1 | INHIBITORS OF THROMBOSIS | CORVAS INT INC (US) | 1998-09-30 | — | — | EP | disclosed |
| US-5492895-A | PEPTIDE ALDEHYDE ANALOGS | CORVAS INTERNATIONAL, INC. (US) | 1996-02-20 | — | — | US | disclosed |