Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363265 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Hydrochloric Acid SCHEMBL28047477 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Hydrochloric Acid SCHEMBL27491870 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL13508575 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29818200 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL21590341 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL31628129 | 0.75 | CES1 (0.52) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28316789 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3828592 | 0.75 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29713752 | 0.75 | HDAC1 (0.36) | ALDH1A1MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461317-A2 | PROCESS FOR PREPARING HYDROXYPYRROLIDINYL ETHYLAMINE COMPOUNDS USEFUL AS KAPPA AGONISTS | Pfizer Products Inc. (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2002088082-A2 | PROCESS FOR PREPARING HYDROXYPYRROLIDINYL ETHYLAMINE COMPOUNDS USEFUL AS KAPPA AGONISTS | PFIZER PRODUCTS INC. (US) | 2002-11-07 | — | — | WO | disclosed |