Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3655522 | 0.98 | KDM4E (0.48) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| Oxalic Acid SCHEMBL3653917 | 0.94 | BCAT2 (0.46) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL7874452 | 0.83 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL4735612 | 0.82 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL7134588 | 0.82 | TSHR (0.54) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL28801221 | 0.81 | CTSD (0.52) | KDM4EALDH1A1MAPTHPGDBCAT2 | |
| SCHEMBL28505829 | 0.80 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL30839543 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL2285452 | 0.80 | BCAT2 (0.44) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL162322 | 0.80 | MAPT (0.52) | KDM4EALDH1A1MAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475550-A | CRAC channel inhibitor composition | CALCIMEDICA INC | 2019-11-19 | — | — | CN | claimed |
| CN-109999036-A | For treating the antiandrogen of non-metastatic castration-resistant prostate cancer | 阿拉贡药品公司 | 2019-07-12 | — | — | CN | claimed |
| CN-109908114-A | For treating the antiandrogen of non-metastatic castration-resistant prostate cancer | 阿拉贡药品公司 | 2019-06-21 | — | — | CN | claimed |
| CN-107530333-A | Treatment of pancreatitis | 钙医学公司 | 2018-01-02 | — | — | CN | claimed |
| CN-104430357-A | Bactericide composition containing coumoxystrobin with synergistic effect | JILIN BADA PESTICIDE CO LTD | 2015-03-25 | — | — | CN | claimed |
| US-11618753-B2 | Aminopyrrolotriazines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-04-04 | — | — | US | disclosed |
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-11-05 | — | — | US | disclosed |
| CN-110475550-A | CRAC channel inhibitor composition | CALCIMEDICA INC | 2019-11-19 | — | — | CN | disclosed |
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-105683178-B | triazine derivatives | 卡尔那生物科学株式会社 | 2019-04-12 | — | — | CN | disclosed |
| CN-104447727-B | Substituted amino-metadiazine compound and its application method and purposes | 广东东阳光药业有限公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-104844589-B | A kind of PI3K kinase inhibitors | 中国科学院合肥物质科学研究院 | 2018-04-20 | — | — | CN | disclosed |
| CN-103749479-A | Sterilization composition containing 2-cyan-3-amino-3-phenylacrylate and amide bactericides | SHAANXI SUNGER ROAD BIO SCI CO | 2014-04-30 | — | — | CN | disclosed |
| CN-103748088-A | Tyrosine Kinase Inhibitors | HOFFMANN LA ROCHE | 2014-04-23 | — | — | CN | disclosed |
| CN-102771502-B | Bactericidal composition containing cyanomycolate and amide bactericide | SHAANXI SUNGER ROAD BIO SCI CO | 2014-03-19 | — | — | CN | disclosed |
| EP-2102177-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Boehringer Ingelheim International GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008071944-A1 | BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
| US-7253198-B2 | Hydroxyethylamine derivatives for the treatment of Alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2007-08-07 | — | — | US | disclosed |
| US-20060025459-A1 | Hydroxyethylamine derivatives for the treatment of alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2006-02-02 | — | — | US | disclosed |
| CN-1425008-A | 3-aminoquinazolin-2, 4-dione antibacterial agents | WARNER LAMBERT CO (US) | 2003-06-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | RIPK1, RIPK2, RIPK4 | KDM4E 1830/4885ALDH1A1 4108/4885MAPT 2052/4885 |
| US-20060025459-A1 | Hydroxyethylamine derivatives for the treatment of alzheimer's disease | BACE2, PSEN2, BACE1 | KDM4E 1129/4885ALDH1A1 3102/4885MAPT 16/4885 |
| US-11618753-B2 | Aminopyrrolotriazines as kinase inhibitors | RIPK1, RIPK2, RIPK4 | KDM4E 1830/4885ALDH1A1 4108/4885MAPT 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.