Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 5/20 | 0.33 |
| ▸ | FNTB | P49356 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672415 | 0.86 | NR3C1 (0.39) | NR3C1PGRNR3C2FNTAFNTB | |
| SCHEMBL5324035 | 0.72 | KDM4E (0.54) | FNTAFNTBMAPTMEN1KMT2A | |
| SCHEMBL5324040 | 0.72 | KDM4E (0.54) | FNTAFNTBMAPTMEN1KMT2A | |
| SCHEMBL3450569 | 0.71 | NCEH1 (0.34) | HTTTACR1MAPTMEN1KMT2A | |
| SCHEMBL7941005 | 0.71 | NCEH1 (0.34) | HTTTACR1MAPTMEN1KMT2A | |
| SCHEMBL11593932 | 0.71 | NCEH1 (0.34) | HTTTACR1MAPTMEN1KMT2A | |
| SCHEMBL20369507 | 0.70 | SLC7A5 (0.49) | MAPTALDH1A1 | |
| SCHEMBL10435929 | 0.70 | SLC7A5 (0.49) | MAPTALDH1A1 | |
| SCHEMBL5767473 | 0.70 | ALDH1A1 (0.44) | HTTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11591299 | 0.70 | ALDH1A1 (0.36) | HTTTACR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |