SCHEMBL6673776

SCHEMBL6673776

CC(C)(C)OC(=O)[N+]1(C2CCNCC2)CCC(O)CC1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
PLAT P00750 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7575563 0.87
SCHEMBL4794552 0.80
Hydrochloric Acid SCHEMBL16823825 0.76
SCHEMBL6612990 0.76 SLC6A2 (0.37)
SCHEMBL7093891 0.74 GPR119 (0.52)
SCHEMBL6681927 0.74 SLC6A4 (0.43)
SCHEMBL7103043 0.74 GPR119 (0.41)
SCHEMBL27459045 0.72 CHRM2 (0.43) CHRM2CHRM1CHRM3
SCHEMBL6613065 0.71 SLC6A2 (0.36) CHRM2CHRM1CHRM3
SCHEMBL6620852 0.70 RECQL (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1436280-A1 A PROCESS FOR PREPARING 4-(HYDROXY)- 1,4']BIPIPERIDINYL-L'CARBOXYLIC ACID TERT-BUTYL ESTER AstraZeneca AB (SE) 2004-07-14 EP disclosed
WO-2003031433-A1 A PROCESS FOR PREPARING 4-(HYDROXY)-[1,4']BIPIPERIDINYL-L'CARBOXYLIC ACID TERT-BUTYL ESTER ASTRAZENECA AB (SE) 2003-04-17 WO disclosed
EP-1274701-A1 CHEMICAL COMPOUNDS AstraZeneca AB (SE) 2003-01-15 EP disclosed
WO-2001077101-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2001-10-18 WO disclosed