Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.34 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.34 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.34 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.34 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681927 | 0.85 | SLC6A4 (0.43) | HRH1CCR3 | |
| SCHEMBL7093891 | 0.81 | GPR119 (0.52) | GPR119HRH1HRH3 | |
| SCHEMBL716207 | 0.74 | HRH1 (0.55) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| SCHEMBL6673776 | 0.74 | CHRM2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL2777776 | 0.73 | HRH1 (0.53) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| Hydrochloric Acid SCHEMBL31647127 | 0.73 | HRH1 (0.53) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| SCHEMBL7575563 | 0.72 | — | — | |
| SCHEMBL2774468 | 0.71 | GPR119 (0.71) | GPR119HRH1CCR3HRH3S1PR3 | |
| SCHEMBL6612990 | 0.70 | SLC6A2 (0.37) | HRH1 | |
| SCHEMBL22266021 | 0.69 | GPR119 (0.55) | GPR119CACNA1HGRIN1GRIN2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274701-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001077101-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-10-18 | — | — | WO | disclosed |