Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.52 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103043 | 0.81 | GPR119 (0.41) | GPR119HRH1HRH3 | |
| SCHEMBL6681927 | 0.81 | SLC6A4 (0.43) | HRH1 | |
| SCHEMBL4717235 | 0.77 | HRH1 (0.56) | GPR119SLC9A3HRH1HRH3 | |
| Hydrochloric Acid SCHEMBL4105228 | 0.76 | HRH1 (0.54) | GPR119SLC9A3HRH1HRH3 | |
| SCHEMBL6673776 | 0.74 | CHRM2 (0.36) | — | |
| SCHEMBL2555749 | 0.72 | GPR119 (0.56) | GPR119SLC9A3HRH1HRH3 | |
| SCHEMBL7575563 | 0.72 | — | — | |
| SCHEMBL2555752 | 0.72 | GPR119 (0.56) | GPR119SLC9A3HRH1HRH3 | |
| Hydrochloric Acid SCHEMBL2553809 | 0.71 | GPR119 (0.55) | GPR119SLC9A3HRH1HRH3 | |
| Hydrochloric Acid SCHEMBL14634228 | 0.71 | GPR119 (0.55) | GPR119SLC9A3HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274701-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001077101-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-10-18 | — | — | WO | disclosed |