SCHEMBL6673818

SCHEMBL6673818

NC(=O)CCC(c1ccccc1)(c1ccccc1)C(C(N)=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
HTT P42858 1/20 0.40
KCNN4 O15554 7/20 0.39
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
KCNH2 Q12809 1/20 0.38
KDM4E B2RXH2 2/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
KIF11 P52732 4/20 0.37
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4153935 0.77 CHRM3 (0.55) MAPTKMT2AHTTKCNN4LMNA
SCHEMBL7102456 0.77 MAPT (0.47) MAPTKMT2AHTTKCNN4LMNA
SCHEMBL13865463 0.76 KIF11 (0.55) MAPTKMT2AHTTKIF11
SCHEMBL29730901 0.75 MAPT (0.46) MAPTKMT2AHTTKCNN4LMNA
SCHEMBL2095353 0.73 CYP3A4 (0.53) MAPTKMT2AHTTKCNN4LMNA
SCHEMBL4138872 0.71 CHRM3 (0.54) MAPTKMT2AHTTKCNN4LMNA
Hydrochloric Acid SCHEMBL27310710 0.71 MAPT (0.41) MAPTKMT2AHTTKCNN4CYP2D6
SCHEMBL4873449 0.71 CYP2C19 (0.47) MAPTLMNACYP2D6KIF11CYP2C19
SCHEMBL8521296 0.71 MAPT (0.46) MAPTKMT2AHTTKCNN4LMNA
SCHEMBL17064282 0.70 MAPT (0.44) MAPTKMT2AHTTKCNN4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004038497-A1 ELECTROPHORETIC DISPLAY AND PROCESS FOR PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2004-05-06 WO disclosed