SCHEMBL6673983

SCHEMBL6673983

CC[Si](CC)(CC)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.49
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
DRD2 P14416 1/20 0.39
DRD4 P21917 1/20 0.39
DRD3 P35462 1/20 0.39
HTR7 P34969 5/20 0.37
HTR2B P41595 1/20 0.37
PGR P06401 1/20 0.35
MAOA P21397 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
KDR P35968 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7583444 0.86 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL27555872 0.85 PNMT (0.47) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL28078161 0.83 PNMT (0.50) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL5981385 0.80 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6671922 0.80 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL29843943 0.80 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL61027 0.80 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL7577803 0.80 PNMT (0.46) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL27555871 0.80 PNMT (0.43) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL30745575 0.80 PNMT (0.52) PNMTNPC1RAB9ADRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677879-A Catalyst for preparing cycloolefin copolymer, preparation method of cycloolefin copolymer, cycloolefin copolymer and application of cycloolefin copolymer 华为技术有限公司 2023-02-03 CN disclosed
CN-101107260-B Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
CN-101107260-A Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO (JP) 2008-01-16 CN disclosed
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 US disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed