Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197595 | 0.91 | PNMT (0.44) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7583444 | 0.87 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL5981385 | 0.81 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL28078161 | 0.81 | PNMT (0.50) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL8086440 | 0.80 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL6673983 | 0.80 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL27555872 | 0.79 | PNMT (0.47) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7584997 | 0.78 | PNMT (0.41) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7576872 | 0.78 | PNMT (0.41) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL6671922 | 0.78 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | claimed |
| US-6365764-B1 | METALLOCENE COMPOUNDS HAVING TWO FLUORENYL LIGANDS BRIDGED WITH A SINGLE SILICON OR GERMANIUM ATOM | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-04-02 | — | — | US | claimed |
| EP-0729968-A1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1996-09-04 | — | — | EP | claimed |
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | disclosed |
| US-6365764-B1 | METALLOCENE COMPOUNDS HAVING TWO FLUORENYL LIGANDS BRIDGED WITH A SINGLE SILICON OR GERMANIUM ATOM | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-04-02 | — | — | US | disclosed |
| US-6180733-B1 | OLEFIN POLYMERIZATION USING CATALYST COMPRISING THE PRODUCT OF REACTION BETWEEN A GROUP 4 OR 5 METALLOCENE COMPOUND AND AN ALUMOXANE, OPTIONALLY WITH ORGANOALUMINUM OR COMPOUND ABLE TO GIVE A METALLOCENE ALKYL CATION; ATACTIC POLYPROPYLENE | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-01-30 | — | — | US | disclosed |
| US-6054404-A | COORDINATION CATALYST | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-04-25 | — | — | US | disclosed |
| US-5786495-A | HIGH MOLECULAR WEIGHT ATACTIC POLYPROPYLENE POLYMERIZATION CATALYST | MONTELL TECHNOLOGY COMPANY BV (NL) | 1998-07-28 | — | — | US | disclosed |
| EP-0729968-A1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1996-09-04 | — | — | EP | disclosed |