Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.50 |
| ▸ | PLG | P00747 | 9/20 | 0.50 |
| ▸ | F2 | P00734 | 5/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 13/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 13/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.36 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674044 | 0.85 | F10 (0.49) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL6674094 | 0.84 | HRH3 (0.48) | — | |
| SCHEMBL6672764 | 0.82 | F10 (0.45) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL5551732 | 0.78 | MTNR1B (0.50) | — | |
| SCHEMBL6672245 | 0.75 | F10 (0.57) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL2121245 | 0.74 | DRD2 (0.38) | — | |
| SCHEMBL4637685 | 0.74 | NR1H2 (0.39) | — | |
| SCHEMBL5165139 | 0.73 | GRIN1 (0.54) | — | |
| SCHEMBL2124647 | 0.73 | ESR1 (0.44) | — | |
| SCHEMBL6673742 | 0.72 | F10 (0.44) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035544-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |