Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672761 | 0.86 | HRH3 (0.45) | HRH3 | |
| SCHEMBL6673737 | 0.86 | F10 (0.44) | HRH3 | |
| SCHEMBL6674094 | 0.83 | HRH3 (0.48) | HRH3 | |
| SCHEMBL5551729 | 0.81 | ESR1 (0.47) | — | |
| SCHEMBL6674044 | 0.81 | F10 (0.49) | HRH3 | |
| SCHEMBL5713459 | 0.78 | GHSR (0.44) | HRH3 | |
| SCHEMBL2121244 | 0.78 | ESR1 (0.40) | — | |
| SCHEMBL4637682 | 0.76 | NR1H2 (0.46) | — | |
| SCHEMBL2124644 | 0.75 | ESR2 (0.45) | — | |
| SCHEMBL5165131 | 0.75 | GRIN1 (0.54) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035544-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |