Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674092 | 0.86 | HRH3 (0.48) | HRH3 | |
| SCHEMBL6673742 | 0.85 | F10 (0.44) | F10ACACBHRH3SLC6A4ITGB3 | |
| SCHEMBL5551729 | 0.79 | ESR1 (0.47) | ABHD6 | |
| SCHEMBL5165131 | 0.79 | GRIN1 (0.54) | HRH3 | |
| SCHEMBL2121244 | 0.76 | ESR1 (0.40) | ABHD6 | |
| SCHEMBL5713459 | 0.76 | GHSR (0.44) | HRH3 | |
| SCHEMBL6672761 | 0.74 | HRH3 (0.45) | F10HRH3ITGB3ITGA2B | |
| SCHEMBL2124644 | 0.73 | ESR2 (0.45) | — | |
| SCHEMBL5713465 | 0.72 | HRH3 (0.39) | HRH3 | |
| SCHEMBL5170173 | 0.72 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035544-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |