Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenyripol SCHEMBL828783 | 0.82 | CYP2D6 (0.70) | ADRB2RAB9AKDM4ECYP2D6 | |
| Fenyripol SCHEMBL120829 | 0.80 | CYP2D6 (0.68) | ADRB2RAB9ALMNAKDM4ECYP2D6 | |
| SCHEMBL22953698 | 0.78 | HIF1A (0.73) | HIF1AADRB1ADRA1AADRB2HTR1A | |
| Phenylephrine SCHEMBL143879 | 0.76 | HIF1A (0.93) | HIF1AADRB1ADRA1AADRB2HTR1A | |
| Phenylephrine SCHEMBL1650043 | 0.76 | HIF1A (0.93) | HIF1AADRB1ADRA1AADRB2HTR1A | |
| Phenylephrine SCHEMBL4712 | 0.75 | HIF1A (1.00) | HIF1AADRB1ADRA1AADRB2HTR1A | |
| Phenylephrine SCHEMBL29382851 | 0.75 | HIF1A (1.00) | HIF1AADRB1ADRA1AADRB2HTR1A | |
| Phenylephrine SCHEMBL895602 | 0.75 | HIF1A (1.00) | HIF1AADRB1ADRA1AADRB2HTR1A | |
| Phenylephrine SCHEMBL29374674 | 0.75 | HIF1A (1.00) | HIF1AADRB1ADRA1AADRB2HTR1A | |
| Phenylephrine SCHEMBL29392606 | 0.75 | HIF1A (1.00) | HIF1AADRB1ADRA1AADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417196-A1 | DNA-PK INHIBITORS | Cancer Research Technology Limited (GB) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003024949-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |