Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918046 | 0.81 | GRIA1 (0.56) | GRIA1GRIA3PDE4DGABRA1GABRG2 | |
| Water SCHEMBL4777578 | 0.81 | GRIA1 (0.56) | GRIA1GRIA3PDE4DGABRA1GABRG2 | |
| SCHEMBL6689015 | 0.77 | PRKDC (0.41) | KMT2AKDM4EALDH1A1F10 | |
| SCHEMBL3667254 | 0.77 | GRIA1 (0.41) | GRIA1GRIA3PDE4DCTSAKDM4E | |
| SCHEMBL3681524 | 0.73 | CYP11B1 (0.45) | GRIA1GRIA3PDE4DGABRA1GABRG2 | |
| SCHEMBL1881068 | 0.73 | GRIA1 (0.64) | GRIA1GRIA3PDE4DKMT2AGRM4 | |
| SCHEMBL3676538 | 0.72 | PTPRC (0.39) | GRIA1GRIA3PDE4DMAOBGABRA1 | |
| SCHEMBL3672704 | 0.71 | GABRG2 (0.43) | GRIA1GRIA3PDE4DF10GABRA1 | |
| SCHEMBL3667717 | 0.70 | PGR (0.44) | MAOBKDM4EALDH1A1 | |
| SCHEMBL2497621 | 0.70 | GABRA1 (0.43) | GRIA1GRIA3PDE4DGRM4GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465626-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES | Eisai Co., Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003047577-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES | EISAI CO LTD (JP) | 2003-06-12 | — | — | WO | disclosed |