Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6679828 | 0.99 | ADRA1A (0.44) | ADRA1ATAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6675209 | 0.81 | FAAH (0.40) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL6676245 | 0.80 | PTGIR (0.49) | ADRA1ATAAR1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6679353 | 0.79 | PTGIR (0.48) | ADRA1ATAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6674471 | 0.79 | ADRA1A (0.45) | ADRA1ATAAR1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6679823 | 0.78 | ADRA1A (0.44) | ADRA1ATAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL11879049 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL13804183 | 0.73 | TAAR1 (0.60) | ADRA1ATAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6680994 | 0.73 | SMN1; SMN2 (0.40) | TAAR1ALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL6684016 | 0.72 | SMN1; SMN2 (0.39) | TAAR1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |