Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 5/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676208 | 0.77 | CA2 (0.49) | NQO2IDO1NAMPTLMNAPOLB | |
| SCHEMBL6680495 | 0.76 | NQO2 (0.47) | NQO2IDO1NAMPTMALT1LMNA | |
| SCHEMBL6033875 | 0.75 | NQO2 (0.55) | NQO2IDO1NAMPTMALT1LMNA | |
| SCHEMBL4381773 | 0.74 | NQO2 (0.61) | NQO2IDO1NAMPTMALT1LMNA | |
| SCHEMBL21680877 | 0.74 | NQO2 (0.57) | NQO2IDO1NAMPTMALT1LMNA | |
| SCHEMBL5757395 | 0.74 | POLB (0.47) | LMNAPOLBTSHR | |
| SCHEMBL5670782 | 0.74 | MTNR1A (0.51) | NQO2IDO1LMNAMEN1TSHR | |
| SCHEMBL1579453 | 0.74 | NQO2 (0.75) | NQO2 | |
| SCHEMBL30898244 | 0.73 | NQO2 (0.57) | NQO2IDO1NAMPTMALT1LMNA | |
| SCHEMBL29242665 | 0.73 | NQO2 (0.54) | NQO2IDO1NAMPTMALT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |