SCHEMBL6674598

SCHEMBL6674598

CCCCCc1c[c]c(OC)c(CCCCC)c1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 8/20 0.41
ALOX5 P09917 7/20 0.41
CYP3A4 P08684 1/20 0.38
HTR2A P28223 1/20 0.38
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
APAF1 O14727 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6674539 0.79 CNR1 (0.36) PTGS2CYP3A4APAF1MAPTTHRB
SCHEMBL27993216 0.76 PTGS2 (0.43) PTGS2ALOX5CYP3A4HTR2AMAPT
SCHEMBL17005869 0.72 HPGD (0.37) PTGS2CYP3A4MAPK1HTT
SCHEMBL7842427 0.69 TYR (0.33) PTGS2ALOX5HTR2A
SCHEMBL9070266 0.69 PPARG (0.55) PTGS2ALOX5HTR2APPARGPPARA
SCHEMBL10609157 0.69 CA2 (0.46) PTGS2ALOX5CYP3A4HTR2APPARA
SCHEMBL9478216 0.68 ESR1 (0.46) PTGS2CYP3A4HTR2APPARGPPARA
SCHEMBL14122353 0.68 PPARG (0.57) PTGS2ALOX5HTR2APPARGPPARA
SCHEMBL7690734 0.68 ESR1 (0.46) PTGS2CYP3A4HTR2APPARGPPARA
SCHEMBL170953 0.68 PTGS2 (0.50) PTGS2CYP3A4HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed