Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024175 | 0.78 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL9346100 | 0.76 | ALOX5 (0.35) | ALOX5PTGS2 | |
| SCHEMBL6024098 | 0.75 | HMGCR (0.33) | — | |
| SCHEMBL3549529 | 0.71 | ALOX5 (0.39) | ALOX5PTGS2HTR2A | |
| SCHEMBL6023945 | 0.70 | HMGCR (0.35) | — | |
| SCHEMBL6674598 | 0.69 | PTGS2 (0.41) | ALOX5PTGS2HTR2A | |
| SCHEMBL1012043 | 0.68 | ALOX5 (0.42) | TYRALOX5PTGS2 | |
| SCHEMBL6023274 | 0.67 | TCF4 (0.33) | — | |
| SCHEMBL16829571 | 0.67 | ALOX5 (0.53) | ALOX5PTGS2 | |
| SCHEMBL27586556 | 0.67 | AOC3 (0.57) | ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083874-A1 | SMALL MOLECULE PIPECOLIC ACID DERIVATIVE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062491-A1 | SMALL MOLECULE PIPECOLIC ACID DERIVATIVE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |