Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | PTGIR | P43119 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681985 | 0.86 | PTGIR (0.40) | CACNA1CSCN5APTGIRADRA2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7241203 | 0.85 | ADRA2A (0.40) | CACNA1CSCN5APTGIRADRA2ASIGMAR1 | |
| SCHEMBL6676322 | 0.82 | ADRA2A (0.45) | CACNA1CSCN5APTGIRADRA2A | |
| SCHEMBL6674705 | 0.81 | HTT (0.37) | HTTHPGDGABRPGABRDGABRA1 | |
| SCHEMBL6675982 | 0.81 | PTGIR (0.38) | CACNA1CSCN5APTGIRADRA2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6678015 | 0.81 | ADRA2A (0.47) | CACNA1CSCN5APTGIRADRA2ASIGMAR1 | |
| SCHEMBL6674908 | 0.80 | PTGIR (0.42) | CACNA1CSCN5APTGIRADRA2A | |
| SCHEMBL6676123 | 0.80 | KCNK3 (0.50) | CACNA1CSCN5A | |
| Hydrochloric Acid SCHEMBL6680944 | 0.79 | ADRA2A (0.42) | CACNA1CSCN5APTGIRADRA2A | |
| SCHEMBL6678176 | 0.75 | PTGIR (0.47) | CACNA1CSCN5APTGIRADRA2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |