Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6674495 | 0.99 | SIGMAR1 (0.38) | PTGIRSIGMAR1C5AR1CACNA1CSCN5A | |
| SCHEMBL6674908 | 0.86 | PTGIR (0.42) | PTGIRCACNA1CSCN5AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6680944 | 0.84 | ADRA2A (0.42) | PTGIRCACNA1CSCN5AADRA2AADRA2B | |
| SCHEMBL6676322 | 0.83 | ADRA2A (0.45) | PTGIRCACNA1CSCN5AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6678015 | 0.82 | ADRA2A (0.47) | PTGIRSIGMAR1CACNA1CSCN5AADRA2A | |
| SCHEMBL6674709 | 0.81 | CACNA1C (0.39) | PTGIRSIGMAR1CACNA1CSCN5AADRA2A | |
| SCHEMBL6675976 | 0.81 | NR1H4 (0.37) | NR1H4CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6674491 | 0.80 | NR1H4 (0.36) | NR1H4CA12CA1CA2CA9 | |
| SCHEMBL27544117 | 0.79 | NR1H4 (0.35) | NR1H4CA12CA1CA2CA9 | |
| SCHEMBL6681985 | 0.78 | PTGIR (0.40) | PTGIRSIGMAR1CACNA1CSCN5AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |