Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 13/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6680944 | 0.99 | ADRA2A (0.42) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6676322 | 0.89 | ADRA2A (0.45) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| Hydrochloric Acid SCHEMBL6678015 | 0.88 | ADRA2A (0.47) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6675982 | 0.86 | PTGIR (0.38) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| Hydrochloric Acid SCHEMBL6674495 | 0.85 | SIGMAR1 (0.38) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6681985 | 0.84 | PTGIR (0.40) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| Hydrochloric Acid SCHEMBL7241203 | 0.83 | ADRA2A (0.40) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6674709 | 0.80 | CACNA1C (0.39) | PTGIRADRA2ACACNA1CSCN5A | |
| SCHEMBL6676318 | 0.79 | PTGIR (0.47) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6676057 | 0.79 | PTGIR (0.47) | PTGIRADRA2AADRA2BADRA2CCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |