Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604563 | 0.81 | KDM4E (0.46) | MEN1KMT2AHTTRAB9ANCF1 | |
| SCHEMBL6600666 | 0.80 | NCF1 (0.49) | MEN1KMT2APIM1PIM3NCF1 | |
| Hydrochloric Acid SCHEMBL6079350 | 0.80 | KDM4E (0.44) | MEN1KMT2AHTTRAB9ANCF1 | |
| Hydrochloric Acid SCHEMBL6080392 | 0.79 | NCF1 (0.48) | MEN1KMT2AHTTPIM1PIM3 | |
| SCHEMBL6594902 | 0.76 | MAPT (0.58) | MEN1KMT2ANPC1HTTRAB9A | |
| SCHEMBL6594911 | 0.76 | MAPT (0.58) | MEN1KMT2ANPC1HTTRAB9A | |
| SCHEMBL6594774 | 0.75 | SMN1; SMN2 (0.46) | MEN1KMT2ANPC1RAB9AADORA3 | |
| SCHEMBL18733034 | 0.74 | CSNK2A2 (0.42) | MEN1KMT2ANPC1HTTRAB9A | |
| SCHEMBL6673204 | 0.73 | SIRT2 (0.43) | MEN1KMT2AKDM4ECSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL6080061 | 0.72 | CSNK2A2 (0.44) | MEN1KMT2ANPC1HTTPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |