Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250361 | 1.00 | POLB (0.40) | POLBALDH1A1LMNAKMT2ATRPV1 | |
| SCHEMBL5254332 | 0.79 | POLB (0.44) | POLBALDH1A1LMNAKMT2ATRPV1 | |
| SCHEMBL5254334 | 0.79 | POLB (0.44) | POLBALDH1A1LMNAKMT2ATRPV1 | |
| SCHEMBL3247575 | 0.78 | POLB (0.42) | POLBALDH1A1LMNAKMT2ATRPV1 | |
| SCHEMBL12321559 | 0.77 | GPR119 (0.50) | LMNATACR1GPR119 | |
| SCHEMBL16341485 | 0.77 | GPR119 (0.50) | LMNATACR1GPR119 | |
| SCHEMBL31363391 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAKMT2AHTTMEN1 | |
| SCHEMBL3247665 | 0.75 | ATM (0.41) | POLBALDH1A1LMNAKMT2ATRPV1 | |
| SCHEMBL6650739 | 0.75 | ATM (0.41) | POLBALDH1A1LMNAKMT2ATRPV1 | |
| SCHEMBL5255027 | 0.73 | DPP4 (0.44) | ALDH1A1LMNAKMT2ATRPV1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470125-A1 | AMINOPIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064421-A1 | AMINOPIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |