Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CTSE | P14091 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12321559 | 0.89 | GPR119 (0.50) | TP53LMNASTSGPR119 | |
| SCHEMBL16341485 | 0.89 | GPR119 (0.50) | TP53LMNASTSGPR119 | |
| SCHEMBL29795366 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TP53EPHX2LMNAMAPT | |
| SCHEMBL7381166 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TP53EPHX2LMNAMAPT | |
| SCHEMBL2308747 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TP53EPHX2LMNAMAPT | |
| SCHEMBL8310166 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TP53EPHX2LMNAMAPT | |
| SCHEMBL20794795 | 0.78 | DNMT3A (0.46) | TP53GPR119MEN1KMT2AMMP13 | |
| SCHEMBL20778648 | 0.78 | DNMT3A (0.46) | TP53GPR119MEN1KMT2AMMP13 | |
| SCHEMBL20766014 | 0.78 | DNMT3A (0.46) | TP53GPR119MEN1KMT2AMMP13 | |
| SCHEMBL29673228 | 0.78 | DNMT3A (0.46) | TP53GPR119MEN1KMT2AMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |