Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679292 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL5887787 | 0.78 | CYP3A4 (0.43) | ALDH1A1TDP1MEN1MAPTKMT2A | |
| SCHEMBL5887762 | 0.76 | CA4 (0.59) | ALDH1A1TDP1KMT2AKDM4ERAB9A | |
| SCHEMBL6681950 | 0.75 | CA1 (0.65) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL10944675 | 0.72 | CYP3A4 (0.53) | ALDH1A1TDP1MEN1MAPTKMT2A | |
| SCHEMBL11403195 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL6676066 | 0.67 | CA4 (0.59) | ALDH1A1TDP1KDM4ERAB9AMAPK1 | |
| SCHEMBL395088 | 0.67 | ABL1 (0.60) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL1339106 | 0.67 | ALDH1A1 (0.61) | ALDH1A1TDP1MEN1MAPTTHRB | |
| SCHEMBL30958575 | 0.67 | GPR3 (0.44) | ALDH1A1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004047925-A2 | THERAPEUTIC OXIDATION CATALYSTS | EXETER ANTIOXIDANT THERAPEUTICS LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |