Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GALR2 | O43603 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6684651 | 0.99 | PNMT (0.38) | PNMTGPR35MEN1KMT2ABPTF | |
| SCHEMBL6676232 | 0.86 | MAPT (0.35) | MEN1KMT2AALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL6684659 | 0.84 | MAPT (0.34) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL7246948 | 0.83 | ALDH1A1 (0.33) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6675316 | 0.77 | PNMT (0.41) | PNMTGPR35MEN1KMT2ABPTF | |
| SCHEMBL27477071 | 0.77 | PNMT (0.41) | PNMTGPR35MEN1KMT2ABPTF | |
| Hydrochloric Acid SCHEMBL27544138 | 0.75 | PNMT (0.40) | PNMTGPR35MEN1KMT2ABPTF | |
| Hydrochloric Acid SCHEMBL6674248 | 0.75 | PNMT (0.40) | PNMTGPR35MEN1KMT2ABPTF | |
| SCHEMBL6675317 | 0.72 | CACNA1C (0.49) | PNMTGPR35MEN1KMT2ABPTF | |
| Hydrochloric Acid SCHEMBL6674250 | 0.71 | CACNA1C (0.48) | PNMTGPR35MEN1KMT2AGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |