Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6684659 | 0.99 | MAPT (0.34) | MAPTKMT2ALMNAHPGDALOX12 | |
| SCHEMBL6675210 | 0.86 | PNMT (0.39) | MAPTKMT2ALMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6684651 | 0.84 | PNMT (0.38) | MAPTKMT2ALMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7246948 | 0.83 | ALDH1A1 (0.33) | MAPTKMT2AALDH1A1GAATP53 | |
| SCHEMBL6676422 | 0.77 | ALDH1A1 (0.42) | MAPTKMT2ALMNAHPGDALOX12 | |
| SCHEMBL6677280 | 0.76 | LMNA (0.34) | KMT2ALMNAHPGDALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6675363 | 0.75 | ALDH1A1 (0.41) | MAPTKMT2ALMNAHPGDALOX12 | |
| SCHEMBL6676424 | 0.71 | CACNA1C (0.48) | MAPTKMT2ALMNAHPGDALOX12 | |
| Hydrochloric Acid SCHEMBL6675369 | 0.70 | CACNA1C (0.47) | MAPTKMT2ALMNAHPGDALOX12 | |
| SCHEMBL6676235 | 0.70 | ALDH1A1 (0.41) | MAPTKMT2ALMNAHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |