Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680406 | 0.78 | KDM4E (0.50) | KDM4EMAPTTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6675265 | 0.76 | CYP19A1 (0.47) | KDM4EMAPTBLMTDP1ALDH1A1 | |
| SCHEMBL8896916 | 0.71 | GRIN2D (0.59) | KDM4EMAPTBLMTDP1ALDH1A1 | |
| SCHEMBL6682269 | 0.70 | CA12 (0.48) | KDM4EMAPTBLMTDP1PARP1 | |
| SCHEMBL8896271 | 0.70 | GRIN2D (0.73) | KDM4EMAPTBLMTDP1GRIN2D | |
| SCHEMBL6678538 | 0.70 | AR (0.57) | KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7983954 | 0.68 | ALDH1A1 (0.70) | KDM4EMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28396699 | 0.68 | TP53 (0.50) | KDM4EMAPTTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7786500 | 0.67 | GRIN2D (0.74) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL27944806 | 0.66 | GRIN2D (0.67) | MAPTBLMTDP1HPGDGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181341-B1 | LUMINESCENT 4-TRIFLUOROMETHYL-2-QUINOLONES WITH LONG-WAVE UV-ABSORPTION AND THE USE THEREOF | URAY GEORG (AT) | 2004-10-27 | — | — | EP | disclosed |
| US-6635759-B2 | Used as luminescent marker for peptides, proteins, RNA and DNA, as complexing agent | Uray, Georg (AT) | 2003-10-21 | — | — | US | disclosed |
| US-20020058793-A1 | Luminescent 4-trifluoromethy1-2-quinolones with long wave UV absorption and their use | AGILENT TECHNOLOGIES, INC. | 2002-05-16 | — | — | US | disclosed |
| EP-1181341-A2 | LUMINESCENT 4-TRIFLUOROMETHYL-2-QUINOLONES WITH LONG-WAVE UV-ABSORPTION AND THE USE THEREOF | Uray, Georg (AT) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000066680-A2 | LUMINESCENT 4-TRIFLUOROMETHYL-2-QUINOLONES WITH LONG-WAVE UV-ABSORPTION AND THE USE THEREOF | URAY GEORG (AT) | 2000-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058793-A1 | Luminescent 4-trifluoromethy1-2-quinolones with long wave UV absorption and their use | CYP4F2, CYP4F12, CRY1 | KDM4E 1871/4885MAPT 2109/4885BLM 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.