Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | APEX1 | P27695 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531326 | 1.00 | TAAR1 (0.64) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL7151036 | 1.00 | TAAR1 (0.64) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| Hydrochloric Acid SCHEMBL4784091 | 0.98 | TDP1 (0.65) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL4074768 | 0.87 | TAAR1 (0.80) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL6923821 | 0.82 | TAAR1 (0.43) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL7490714 | 0.81 | TAAR1 (0.64) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL9729120 | 0.78 | TAAR1 (0.67) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL13880000 | 0.78 | TAAR1 (0.67) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL6134241 | 0.78 | TSHR (0.46) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL6493189 | 0.78 | TSHR (0.46) | TAAR1NFKB1TSHRHIF1AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632972-B2 | Reacting an acid and an amine; apoptosis; carbamate, and N-phenethyl-2-phenylacetamide | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLIONIS (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632972-B2 | Reacting an acid and an amine; apoptosis; carbamate, and N-phenethyl-2-phenylacetamide | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLIONIS (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1204636-B1 | 3-OXOPROPANE-1-SULPHONIC ACIDS AND SULPHONATES | DSM IP ASSETS BV (NL) | 2004-10-27 | — | — | EP | disclosed |
| US-6639103-B1 | Enantiomerically enriched forms; resolving amino functiona-lized enantiomers | DSM N.V. (NL) | 2003-10-28 | — | — | US | disclosed |