SCHEMBL6675757

SCHEMBL6675757

CCCOc1ccccc1-c1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.52
MAPT P10636 4/20 0.52
JAK2 O60674 1/20 0.52
GAA P10253 1/20 0.52
ALDH1A1 P00352 3/20 0.50
HTT P42858 2/20 0.50
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HTR7 P34969 2/20 0.45
PDE5A O76074 4/20 0.44
PDE4A P27815 2/20 0.44
PDE4B Q07343 2/20 0.44
PDE4C Q08493 2/20 0.44
PDE4D Q08499 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
CYP1A2 P05177 3/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP19A1 P11511 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10438816 0.88 HTR7 (0.53) LMNAMAPTALDH1A1HTR7PDE5A
SCHEMBL9123355 0.88 LMNA (0.53) LMNAMAPTJAK2GAAPDE5A
SCHEMBL28161195 0.88 LMNA (0.47) LMNAMAPTJAK2GAAALDH1A1
SCHEMBL27980667 0.88 LMNA (0.53) LMNAMAPTJAK2GAAPDE5A
SCHEMBL9257284 0.88 LMNA (0.53) LMNAMAPTJAK2GAAPDE5A
SCHEMBL27317852 0.86 LMNA (0.57) LMNAMAPTJAK2GAAALDH1A1
SCHEMBL3883588 0.85 MEN1 (0.51) LMNAMAPTJAK2GAAALDH1A1
1-Hydroxy-2-Propoxybenzene SCHEMBL1805086 0.84 GAA (0.72) LMNAMAPTJAK2GAAALDH1A1
SCHEMBL27555571 0.84 GAA (0.55) LMNAMAPTJAK2GAAHTR7
SCHEMBL904496 0.83 LMNA (0.53) LMNAMAPTJAK2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
CN-113574041-A Method for producing bisphenol and method for producing polycarbonate resin 三菱化学株式会社 2021-10-29 CN disclosed
WO-2020189201-A1 METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-24 WO disclosed
CN-1178906-C N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases ���Ͽع����޹�˾ 2004-12-08 CN disclosed
EP-1420771-A2 USE OF TRIFLUOROACETYL ALKYL-SUBSTITUTED PHENYL DERIVATIVES, PHENOL DERIVATIVES, AND BENZOYL DERIVATIVES IN THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY AND ACCOMPANYING DISEASES AND/OR SECONDARY DISEASES Solvay Pharmaceuticals GmbH (DE) 2004-05-26 EP disclosed
WO-2003007923-A2 USE OF TRIFLUOROACETYL ALKYL-SUBSTITUTED PHENYL DERIVATIVES, PHENOL DERIVATIVES, AND BENZOYL DERIVATIVES IN THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY AND ACCOMPANYING DISEASES AND/OR SECONDARY DISEASES SOLVAY PHARMACEUTICALS GMBH (DE) 2003-01-30 WO disclosed
CN-1261876-A N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases ABBOTT LAB (US) 2000-08-02 CN disclosed