Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938309 | 0.90 | TP53 (0.57) | LMNAIDO1TP53MAPK1RAB9A | |
| SCHEMBL27317852 | 0.88 | LMNA (0.57) | LMNAJAK2GAAMAPTIDO1 | |
| SCHEMBL1030614 | 0.84 | GAA (0.75) | LMNAJAK2GAAMAPTIDO1 | |
| SCHEMBL6675757 | 0.83 | LMNA (0.52) | LMNAJAK2GAAMAPTTP53 | |
| SCHEMBL8736657 | 0.83 | LMNA (0.52) | LMNAJAK2GAAMAPTIDO1 | |
| SCHEMBL29418129 | 0.82 | TP53 (0.69) | LMNATP53MAPK1RAB9AALDH1A1 | |
| SCHEMBL159005 | 0.82 | TP53 (0.69) | LMNATP53MAPK1RAB9AALDH1A1 | |
| SCHEMBL27555571 | 0.81 | GAA (0.55) | LMNAJAK2GAAMAPTTP53 | |
| Di(Hydroxyethyl)Ether SCHEMBL10631967 | 0.79 | ALDH1A1 (0.50) | LMNAJAK2GAAMAPTIDO1 | |
| SCHEMBL9257284 | 0.79 | LMNA (0.53) | LMNAJAK2GAAMAPTPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946367-B2 | Polymerizable carbamate and thiocarbamate compounds, polymers derived from them, and compositions thereof | ISP INVESTMENTS INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20130090443-A1 | POLYMERIZABLE CARBAMATE AND THIOCARBAMATE COMPOUNDS, POLYMERS DERIVED FROM THEM, AND COMPOSITIONS THEREOF | ISP INVESTMENTS INC. (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2011163317-A2 | POLYMERIZABLE CARBAMATE AND THIOCARBAMATE COMPOUNDS, POLYMERS DERIVED FROM THEM, AND COMPOSITIONS THEREOF | ISP INVESTMENTS INC. (US) | 2011-12-29 | — | — | WO | disclosed |
| EP-0551867-B1 | Laminated transparent plastic material and polymerizable monomer | MITSUI CHEMICALS INC (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5451695-A | Acrylic ester monomer with carbamate group, glazing for windows | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-09-19 | — | — | US | disclosed |
| US-5393607-A | Glazing materials; hardness, impact strength, scratch resistance | MITSUI TOATSU CHEMICLAS, INC. (JP) | 1995-02-28 | — | — | US | disclosed |
| EP-0551867-A1 | Laminated transparent plastic material and polymerizable monomer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090443-A1 | POLYMERIZABLE CARBAMATE AND THIOCARBAMATE COMPOUNDS, POLYMERS DERIVED FROM THEM, AND COMPOSITIONS THEREOF | CUTA, CTH, ACOT7 | LMNA 4550/4885JAK2 4611/4885GAA 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.