SCHEMBL6675829

SCHEMBL6675829

c1ccc(CN(Cc2ccccc2)Cc2ccc3ccccc3c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 3/20 0.59
SLC6A2 P23975 3/20 0.58
SLC6A4 P31645 3/20 0.58
SLC6A3 Q01959 3/20 0.58
CYP1A2 P05177 2/20 0.52
CYP2A6 P11509 1/20 0.52
PYCR1 P32322 1/20 0.50
KMT2A Q03164 1/20 0.50
ACHE P22303 1/20 0.49
CNR2 P34972 1/20 0.48
NR1D1 P20393 1/20 0.48
HDAC3 O15379 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HSP90AB1 P08238 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764499 1.00 BCHE (0.59) BCHESLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL14417370 0.89 BCHE (0.61) BCHESLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL19700314 0.85 BCHE (0.48) BCHESLC6A2SLC6A4SLC6A3HSP90AB1
SCHEMBL5703580 0.84 PYCR1 (0.65) BCHESLC6A2SLC6A4SLC6A3PYCR1
SCHEMBL10039139 0.84 CALM1 (0.62) BCHESLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL17266146 0.84 SLC6A2 (0.55) BCHESLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL5703545 0.82 ACHE (0.49) BCHESLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL12049793 0.82 CNR2 (0.64) CNR2CYP2C19
SCHEMBL20022001 0.82 CYP1A2 (0.61) BCHESLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL2442113 0.81 CYP1A2 (0.56) BCHECYP1A2ACHEHDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004048463-A1 POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS PARODI FABRIZIO (IT) 2004-06-10 WO claimed
CN-110803995-B Method for synthesizing tertiary amine derivative through hydroboration reaction of tertiary amide under catalysis of rare earth 温州医科大学 2022-07-08 CN disclosed
WO-2004048463-A1 POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS PARODI FABRIZIO (IT) 2004-06-10 WO disclosed