Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679182 | 0.81 | RAB9A (0.37) | RAB9AKMT2APOLBALDH1A1TSHR | |
| SCHEMBL6672679 | 0.79 | LMNA (0.46) | RAB9AKMT2APOLBALDH1A1TSHR | |
| SCHEMBL6673801 | 0.78 | ADORA2A (0.39) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6675408 | 0.78 | LMNA (0.42) | RAB9AKMT2APOLBALDH1A1TSHR | |
| SCHEMBL6675467 | 0.77 | SMN1; SMN2 (0.33) | POLBALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL6672660 | 0.77 | LMNA (0.41) | RAB9AKMT2APOLBALDH1A1TSHR | |
| SCHEMBL12620729 | 0.67 | POLB (0.44) | RAB9AKMT2APOLBALDH1A1NPC1 | |
| SCHEMBL14733932 | 0.65 | POLB (0.71) | RAB9AKMT2APOLBALDH1A1NPC1 | |
| SCHEMBL19841 | 0.62 | ADORA2A (0.69) | RAB9AKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11381751 | 0.62 | HTT (0.31) | RAB9AKMT2AALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | disclosed |
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | disclosed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | disclosed |