SCHEMBL6675467

SCHEMBL6675467

CCC(C)Cn1cnc(S)c2ncnc1-2

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6674163 0.82 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1LMNATSHRHTT
SCHEMBL6673801 0.80 ADORA2A (0.39) SMN1; SMN2ALDH1A1LMNAADORA2AADORA1
SCHEMBL6676134 0.77 RAB9A (0.37) SMN1; SMN2ALDH1A1POLBLMNATSHR
SCHEMBL6672679 0.75 LMNA (0.46) SMN1; SMN2ALDH1A1POLBLMNATSHR
SCHEMBL6675408 0.74 LMNA (0.42) SMN1; SMN2ALDH1A1POLBLMNATSHR
SCHEMBL6672660 0.73 LMNA (0.41) SMN1; SMN2ALDH1A1POLBLMNATSHR
SCHEMBL12620729 0.69 POLB (0.44) SMN1; SMN2ALDH1A1POLBLMNAHTT
SCHEMBL13997084 0.66 ADORA2A (0.43) SMN1; SMN2ALDH1A1ADORA2AADORA1
SCHEMBL18782963 0.61 KMT2A (0.52) SMN1; SMN2ALDH1A1POLBLMNATSHR
SCHEMBL13545635 0.60 APAF1 (0.61) SMN1; SMN2POLBLMNATSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1202628-B1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2004-10-13 EP claimed
EP-1202628-A4 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2002-10-30 EP claimed
EP-1202628-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS Euro-Celtique S.A. (LU) 2002-05-08 EP claimed
WO-2001011967-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO-CELTIQUE S.A. (LU) 2001-02-22 WO claimed
EP-1202628-B1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2004-10-13 EP disclosed
EP-1202628-A4 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2002-10-30 EP disclosed
EP-1202628-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS Euro-Celtique S.A. (LU) 2002-05-08 EP disclosed
WO-2001011967-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO-CELTIQUE S.A. (LU) 2001-02-22 WO disclosed