SCHEMBL6674438

SCHEMBL6674438

Cn1cnc(=O)c2[nH]cnc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.62
PIK3C3 Q8NEB9 1/20 0.62
ATAD2 Q6PL18 1/20 0.49
ADORA2A P29274 9/20 0.47
PDE4A P27815 8/20 0.47
PDE4B Q07343 8/20 0.47
PDE4C Q08493 8/20 0.47
PDE4D Q08499 8/20 0.47
ADORA2B P29275 8/20 0.47
ADORA3 P0DMS8 2/20 0.47
ADORA1 P30542 2/20 0.47
PIK3CD O00329 1/20 0.47
ALPL P05186 1/20 0.47
TMIGD3 P0DMS9 1/20 0.47
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
CHIT1 Q13231 1/20 0.43
CHIA Q9BZP6 1/20 0.43
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6676183 0.78 PDE4A (0.53) ADORA2APDE4APDE4BPDE4CPDE4D
SCHEMBL15764619 0.77 PIK3CG (1.00) PIK3CGPIK3C3ATAD2ADORA2APDE4A
SCHEMBL29627044 0.77 PIK3CG (0.41) PIK3CGPIK3C3ATAD2ADORA2APDE4A
SCHEMBL6673126 0.77 ADORA2A (0.49) ATAD2ADORA2APDE4APDE4BPDE4C
SCHEMBL6673901 0.75 ADORA2A (0.52) ADORA2APDE4APDE4BPDE4CPDE4D
SCHEMBL1992701 0.74 HPRT1 (0.54) PIK3CGPIK3C3ADORA2AADORA1
SCHEMBL6679184 0.74 ADORA2B (0.51) ATAD2ADORA2APDE4APDE4BPDE4C
SCHEMBL6673671 0.74 ADORA2B (0.55) ADORA2APDE4APDE4BPDE4CPDE4D
SCHEMBL6673871 0.73 ADORA2B (0.57) ADORA2APDE4APDE4BPDE4CPDE4D
SCHEMBL48434 0.70 ATAD2 (0.54) ATAD2ADORA2APDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1202628-A4 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2002-10-30 EP claimed
EP-1202628-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS Euro-Celtique S.A. (LU) 2002-05-08 EP claimed
WO-2001011967-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO-CELTIQUE S.A. (LU) 2001-02-22 WO claimed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
EP-1202628-B1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2004-10-13 EP disclosed
EP-1202628-A4 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2002-10-30 EP disclosed
EP-1202628-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS Euro-Celtique S.A. (LU) 2002-05-08 EP disclosed
WO-2001011967-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO-CELTIQUE S.A. (LU) 2001-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 PIK3CG 1262/4885PIK3C3 642/4885ATAD2 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.