Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450810 | 0.79 | TSHR (0.47) | P2RX7TSHRTDP1CTSSPOLB | |
| SCHEMBL20115058 | 0.78 | P2RX7 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2220103 | 0.77 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13278030 | 0.75 | CA12 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21708208 | 0.72 | KDM4E (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2221391 | 0.72 | LMNA (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13277862 | 0.71 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5388644 | 0.70 | CA2 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL807279 | 0.69 | P2RX7 (0.48) | CA1CA2P2RX7KDM4ETSHR | |
| SCHEMBL6676453 | 0.69 | AR (0.33) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1290001-B1 | PROCESS FOR THE SELECTIVE DEPROTONATION AND FUNCTIONALIZATION OF 3-SUBSTITUTED BENZOTRIFLUORIDES | DOW AGROSCIENCES LLC (US) | 2004-11-03 | — | — | EP | disclosed |
| US-6462240-B2 | FROMING 2-LITHIOBENZOTRIFLORIDE FROM BENZOTRIFLUORIDE AND ALKYLLITHIUM | DOW AGROSCIENCES LLC | 2002-10-08 | — | — | US | disclosed |
| US-20020010375-A1 | Process for the selective deprotonation and functionalization of 3-substituted benzotrifluorides | CORTEVA AGRISCIENCE LLC | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010375-A1 | Process for the selective deprotonation and functionalization of 3-substituted benzotrifluorides | BPTF, FGFR2, FGFR4 | CA12 736/4885CA1 1244/4885CA2 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.