SCHEMBL6676541

SCHEMBL6676541

COc1ccc(CN(S)C(N)=O)cc1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
LDHA P00338 1/20 0.51
CA2 P00918 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 2/20 0.49
ATM Q13315 1/20 0.49
AOC3 Q16853 1/20 0.47
LMNA P02545 3/20 0.47
TSHR P16473 2/20 0.47
ALOX15 P16050 1/20 0.47
HSP90AA1 P07900 1/20 0.47
ACHE P22303 1/20 0.47
NPC1 O15118 1/20 0.47
HTT P42858 1/20 0.47
CYP19A1 P11511 1/20 0.46
TP53 P04637 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1064750 0.80 ALDH1A1 (0.51) ALDH1A1LDHACA2ACHEHTT
SCHEMBL27963430 0.77 ALDH1A1 (0.48) ALDH1A1LDHACA2L3MBTL1KDM4E
SCHEMBL14237559 0.75 CA2 (0.61) ALDH1A1LDHACA2L3MBTL1KDM4E
SCHEMBL18646103 0.75 HSP90AA1 (0.54) ALDH1A1LDHAKDM4EATMAOC3
SCHEMBL27394200 0.74 ALDH1A1 (0.51) ALDH1A1LDHACA2L3MBTL1KDM4E
SCHEMBL5473440 0.74 HSP90AA1 (0.60) ALDH1A1LDHACA2L3MBTL1KDM4E
SCHEMBL11622239 0.74 MEN1 (0.50) ALDH1A1L3MBTL1AOC3LMNAACHE
SCHEMBL1033641 0.74 LMNA (0.61) ALDH1A1LDHACA2KDM4EATM
SCHEMBL3436222 0.74 AOC3 (0.69) ALDH1A1CA2KDM4EATMAOC3
SCHEMBL29602721 0.74 LMNA (0.61) ALDH1A1LDHACA2KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1202628-B1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2004-10-13 EP disclosed
EP-1202628-A4 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO CELTIQUE SA (LU) 2002-10-30 EP disclosed
EP-1202628-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS Euro-Celtique S.A. (LU) 2002-05-08 EP disclosed
WO-2001011967-A1 NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS EURO-CELTIQUE S.A. (LU) 2001-02-22 WO disclosed