Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 10/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45766 | 1.00 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| Hydrochloric Acid SCHEMBL15923088 | 0.98 | FOLH1 (0.47) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| Acetic Acid SCHEMBL268741 | 0.95 | FOLH1 (0.45) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL232126 | 0.95 | FOLH1 (0.42) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL3433410 | 0.95 | FOLH1 (0.42) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL27799398 | 0.95 | FOLH1 (0.42) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| Hydrochloric Acid SCHEMBL15923983 | 0.93 | FOLH1 (0.41) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL861645 | 0.83 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL861646 | 0.83 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL29666181 | 0.83 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279808-B | Cystic fibrosis transmembrane conductance regulator modulators | 弗特克斯药品有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-112250627-B | Cystic fibrosis transmembrane conductance regulator modulators | 弗特克斯药品有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-106255689-B | Heteroaryl SYK Inhibitors | 勃林格殷格翰国际有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-110183440-A | Heteroaryl SYK inhibitor | 勃林格殷格翰国际有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-107690281-A | Cystic fibrosis transmembrane transduction modulator modulators | 弗特克斯药品有限公司 | 2018-02-13 | — | — | CN | disclosed |
| EP-1278547-B1 | FORMULATIONS AND METHODS OF USING NITRIC OXIDE MIMETICS AGAINST A MALIGNANT CELL PHENOTYPE | CELLEGY PHARMA INC (US) | 2004-11-03 | — | — | EP | disclosed |