Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 11/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666181 | 1.00 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL861646 | 1.00 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL1062835 | 0.95 | FOLH1 (0.42) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL20586820 | 0.95 | FOLH1 (0.42) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL1062834 | 0.95 | FOLH1 (0.42) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL30787971 | 0.87 | GGT1 (0.43) | FOLH1GSRRNPEPGGT1 | |
| SCHEMBL45766 | 0.83 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL6676701 | 0.83 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL11217895 | 0.83 | ALDH1A1 (0.51) | SLC6A5 | |
| Hydrochloric Acid SCHEMBL15923088 | 0.81 | FOLH1 (0.47) | FOLH1GSRRNPEPSLC6A5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1297826-A1 | Nasal pharmaceutical compositions containing a NK-2 antagonist | Menarini Ricerche S.p.A. (IT) | 2003-04-02 | — | — | EP | claimed |
| US-12358948-B2 | Neurotensinergic agonists and methods of using same preventing or treating pain | SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) | 2025-07-15 | — | — | US | disclosed |
| US-20220168383-A1 | NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN | SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) | 2022-06-02 | — | — | US | disclosed |
| EP-3921331-A1 | NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN | Socpra Sciences Santé Et Humaines S.E.C. (CA) | 2021-12-15 | — | — | EP | disclosed |
| CN-113677692-A | Neurotensin agonists and methods of preventing or treating pain using the same | 健康与人类科学公司 | 2021-11-19 | — | — | CN | disclosed |
| US-20210188979-A1 | Therapeutic Nanoparticles Comprising A Therapeutic Agent And Methods of Making and Using Same | PFIZER INC. (US) | 2021-06-24 | — | — | US | disclosed |
| WO-2020160685-A1 | NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2020-08-13 | — | — | WO | disclosed |
| CN-111263659-A | Supramolecular filamentous assemblies for protein purification | 约翰霍普金斯大学 | 2020-06-09 | — | — | CN | disclosed |
| US-20200093827-A1 | Pemetrexed Polymeric Nanoparticles And Methods Of Making And Using Same | PFIZER INC. (US) | 2020-03-26 | — | — | US | disclosed |
| EP-2774608-B1 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER (US) | 2019-11-20 | — | — | EP | disclosed |
| US-20100068286-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | PFIZER INC. | 2010-03-18 | — | — | US | disclosed |
| EP-2162540-A2 | COMPOSITIONS AND METHODS FOR PRODUCING BIOACTIVE FUSION PROTEINS | Amgen Inc. (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2010005721-A2 | DRUG LOADED POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME | BIND BIOSCIENCES, INC. (US) | 2010-01-14 | — | — | WO | disclosed |
| WO-2010005723-A2 | DRUG LOADED POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME | BIND BIOSCIENCES, INC. (US) | 2010-01-14 | — | — | WO | disclosed |
| WO-2008153745-A2 | COMPOSITIONS AND METHODS FOR PRODUCING BIOACTIVE FUSION PROTEINS | AMGEN INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008105759-A1 | METHODS FOR SYNTHESIS OF MODIFIED PEPTIDES | ARGOLYN BIOSCIENCE, INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| CN-1591183-A | Image recording material and planographic printing plate | FUJI PHOTO FILM CO LTD (JP) | 2005-03-09 | — | — | CN | disclosed |
| EP-1297826-A1 | Nasal pharmaceutical compositions containing a NK-2 antagonist | Menarini Ricerche S.p.A. (IT) | 2003-04-02 | — | — | EP | disclosed |
| US-5240913-A | Polypeptide anticoagulants | BIOGEN, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| CN-1072337-A | SKIN CARE CREAM | DAILY CHEMICAL PLANT SUZHOU RU (CN) | 1993-05-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188979-A1 | Therapeutic Nanoparticles Comprising A Therapeutic Agent And Methods of Making and Using Same | CD47, CD274, PDCD1 | FOLH1 8/4885GSR 3136/4885RNPEP 1298/4885 |
| US-12358948-B2 | Neurotensinergic agonists and methods of using same preventing or treating pain | VIP, NTSR2, VIPR2 | FOLH1 609/4885GSR 670/4885RNPEP 1803/4885 |
| US-20200093827-A1 | Pemetrexed Polymeric Nanoparticles And Methods Of Making And Using Same | MTHFD1, TYMP, FPGS | FOLH1 51/4885GSR 1137/4885RNPEP 2400/4885 |
| US-20100068286-A1 | Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same | LDHA, LDHB, LPXN | FOLH1 177/4885GSR 1936/4885RNPEP 2015/4885 |
| US-20220168383-A1 | NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN | VIP, NTSR2, VIPR2 | FOLH1 609/4885GSR 670/4885RNPEP 1803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.