2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL6676818

Oc1nc(O)nc(O)n1.Sc1nc2ccccc2s1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.47
ALDH1A1 P00352 5/20 0.47
NPC1 O15118 5/20 0.47
MAPT P10636 4/20 0.47
KDM4E B2RXH2 4/20 0.47
LMNA P02545 2/20 0.47
GAA P10253 2/20 0.47
GLA P06280 1/20 0.47
HSD17B10 Q99714 3/20 0.46
HPGD P15428 2/20 0.46
ADRA2A P08913 1/20 0.46
FBP1 P09467 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
DRD2 P14416 1/20 0.46
ALOX15 P16050 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
DRD1 P21728 1/20 0.46
MC5R P33032 1/20 0.46
OPRM1 P35372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL23237 0.90 ALDH1A1 (0.54) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL29509878 0.90 ALDH1A1 (0.54) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL3789760 0.90 ALDH1A1 (0.54) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL11575316 0.88 ALDH1A1 (0.52) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL10429471 0.88 ALDH1A1 (0.52) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL8158663 0.88 ALDH1A1 (0.52) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL78798 0.88 ALDH1A1 (0.52) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL20537310 0.88 ALDH1A1 (0.52) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL17684719 0.88 ALDH1A1 (0.52) RAB9AALDH1A1NPC1MAPTKDM4E
2-Mercaptobenzothiazole SCHEMBL8880605 0.88 ALDH1A1 (0.52) RAB9AALDH1A1NPC1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0905163-B1 Acrylic elastomer composition NIPPON MEKTRON KK (JP) 2004-10-27 EP disclosed
US-6015860-A POLYFUNCTIONAL (BLOCKED) ISOCYANATE, GUANIDINE, QUATERNARY AMMONIUM SALT, TERTIARY AMINE, AND TERTIARY PHOSPHINE VULCANIZATION ACCELERATOR; HEAT AND SCORCH RESISTANCE; RESILIENCE NIPPON MEKTRON, LIMITED (JP) 2000-01-18 US disclosed
EP-0905163-A1 Acrylic elastomer composition Nippon Mektron, Limited (JP) 1999-03-31 EP disclosed